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Cell-free expression tools to study co-translational folding of alpha helical membrane transporters
Most helical membrane proteins fold co-translationally during unidirectional polypeptide elongation by the ribosome. Studies thus far, however, have largely focussed on refolding full-length proteins from artificially induced denatured states that are far removed from the natural co-translational pr...
Autores principales: | Harris, Nicola J., Pellowe, Grant A., Booth, Paula J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272624/ https://www.ncbi.nlm.nih.gov/pubmed/32499529 http://dx.doi.org/10.1038/s41598-020-66097-4 |
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