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Cell-free expression tools to study co-translational folding of alpha helical membrane transporters

Most helical membrane proteins fold co-translationally during unidirectional polypeptide elongation by the ribosome. Studies thus far, however, have largely focussed on refolding full-length proteins from artificially induced denatured states that are far removed from the natural co-translational pr...

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Detalles Bibliográficos
Autores principales: Harris, Nicola J., Pellowe, Grant A., Booth, Paula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272624/
https://www.ncbi.nlm.nih.gov/pubmed/32499529
http://dx.doi.org/10.1038/s41598-020-66097-4

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