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Inferring Active Metabolic Pathways from Proteomics and Essentiality Data

Here, we propose an approach to identify active metabolic pathways by integrating gene essentiality analysis and protein abundance. We use two bacterial species (Mycoplasma pneumoniae and Mycoplasma agalactiae) that share a high gene content similarity yet show significant metabolic differences. Fir...

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Detalles Bibliográficos
Autores principales: Montero-Blay, Ariadna, Piñero-Lambea, Carlos, Miravet-Verde, Samuel, Lluch-Senar, Maria, Serrano, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273199/
https://www.ncbi.nlm.nih.gov/pubmed/32492430
http://dx.doi.org/10.1016/j.celrep.2020.107722