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Upper airway gene expression differentiates COVID-19 from other acute respiratory illnesses and reveals suppression of innate immune responses by SARS-CoV-2

We studied the host transcriptional response to SARS-CoV-2 by performing metagenomic sequencing of upper airway samples in 238 patients with COVID-19, other viral or non-viral acute respiratory illnesses (ARIs). Compared to other viral ARIs, COVID-19 was characterized by a diminished innate immune r...

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Detalles Bibliográficos
Autores principales:	Mick, Eran, Kamm, Jack, Pisco, Angela Oliveira, Ratnasiri, Kalani, Babik, Jennifer M., Calfee, Carolyn S., Castañeda, Gloria, DeRisi, Joseph L., Detweiler, Angela M., Hao, Samantha, Kangelaris, Kirsten N., Kumar, G. Renuka, Li, Lucy M., Mann, Sabrina A., Neff, Norma, Prasad, Priya A., Serpa, Paula Hayakawa, Shah, Sachin J., Spottiswoode, Natasha, Tan, Michelle, Christenson, Stephanie A., Kistler, Amy, Langelier, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273244/ https://www.ncbi.nlm.nih.gov/pubmed/32511476 http://dx.doi.org/10.1101/2020.05.18.20105171

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