Cargando…
A SARS-CoV-2 serological assay to determine the presence of blocking antibodies that compete for human ACE2 binding
As SARS-CoV-2 continues to spread around the world, there is an urgent need for new assay formats to characterize the humoral response to infection. Convalescent serum is being used for treatment and for isolation of patient-derived antibodies. However, currently there is not a simple means to estim...
Autores principales: | Byrnes, James R., Zhou, Xin X., Lui, Irene, Elledge, Susanna K., Glasgow, Jeff E., Lim, Shion A., Loudermilk, Rita, Chiu, Charles Y., Wilson, Michael R., Leung, Kevin K., Wells, James A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273274/ https://www.ncbi.nlm.nih.gov/pubmed/32511506 http://dx.doi.org/10.1101/2020.05.27.20114652 |
Ejemplares similares
-
Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding
por: Byrnes, James R., et al.
Publicado: (2020) -
Cell-surface tethered promiscuous biotinylators enable comparative small-scale surface proteomic analysis of human extracellular vesicles and cells
por: Kirkemo, Lisa L, et al.
Publicado: (2022) -
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2
por: Bracken, Colton J., et al.
Publicado: (2020) -
Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection
por: Elledge, Susanna K., et al.
Publicado: (2020) -
Reply to Liu et al.: Specific mutations matter in specificity and catalysis in ACE2
por: Glasgow, Jeff, et al.
Publicado: (2021)