Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: A case series

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BACKGROUND: Mechanically ventilated patients with coronavirus disease 2019 (COVID-19) have a mortality of 24–53%, in part due to distal mucopurulent secretions interfering with ventilation. Dornase alfa is recombinant human DNase 1 and digests DNA in mucoid sputum. Nebulized dornase alfa is FDA-appr...

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Detalles Bibliográficos
Autores principales: Weber, Andrew G., Chau, Alice S., Egeblad, Mikala, Barnes, Betsy J., Janowitz, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273282/
https://www.ncbi.nlm.nih.gov/pubmed/32511514
http://dx.doi.org/10.1101/2020.05.13.20087734
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