Host-Induced Genome Instability Rapidly Generates Phenotypic Variation across Candida albicans Strains and Ploidy States

Candida albicans is an opportunistic fungal pathogen of humans that is typically diploid yet has a highly labile genome tolerant of large-scale perturbations including chromosomal aneuploidy and loss-of-heterozygosity events. The ability to rapidly generate genetic variation is crucial for C. albica...

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Detalles Bibliográficos
Autores principales: Smith, Amanda C., Hickman, Meleah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273350/
https://www.ncbi.nlm.nih.gov/pubmed/32493724
http://dx.doi.org/10.1128/mSphere.00433-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273350/
https://www.ncbi.nlm.nih.gov/pubmed/32493724
http://dx.doi.org/10.1128/mSphere.00433-20

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