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Iron-Chelating Agent Can Maintain Bone Homeostasis Disrupted by Iron Overload by Upregulating Wnt/Beta-Catenin Signaling

BACKGROUND: The incidence of osteoporotic fractures is increasing. In this study, we explored the activities of Wnt/β-catenin signaling in bone tissues with iron accumulation. METHODS: We established rat bipedal walking models (RBWM), and a portion of our RBWM rats were intraperitoneally injected wi...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Yu, Ronghua, Zhu, Xiaodong, Li, Zhikun, Jia, Jianjun, Li, Dachuan, Chen, Yu, Zhang, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273370/
https://www.ncbi.nlm.nih.gov/pubmed/32596380
http://dx.doi.org/10.1155/2020/8256261