Cargando…

Neuroprotective Effect of Chlorogenic Acid on Mitochondrial Dysfunction-Mediated Apoptotic Death of DA Neurons in a Parkinsonian Mouse Model

Mitochondrial dysfunction and oxidative stress characterize major factors involved in the activation of complex processes corresponding to apoptosis-mediated neuronal senescence of dopaminergic neurons (DA) in Parkinson's disease (PD). Here, we evaluated the molecular mechanisms participating i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Saumitra Sen, Rai, Sachchida Nand, Birla, Hareram, Zahra, Walia, Rathore, Aaina Singh, Dilnashin, Hagera, Singh, Richa, Singh, Surya Pratap
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273475/ https://www.ncbi.nlm.nih.gov/pubmed/32566093 http://dx.doi.org/10.1155/2020/6571484

Ejemplares similares

Neuroprotective effects of Withania somnifera in BPA induced-cognitive dysfunction and oxidative stress in mice
por: Birla, Hareram, et al.
Publicado: (2019)

Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway
por: Singh, Richa, et al.
Publicado: (2023)

Commentary: Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease
por: Rai, Sachchida N., et al.
Publicado: (2018)

Commentary: Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease
por: Rai, Sachchida Nand, et al.
Publicado: (2018)

Effect of Chlorogenic Acid Supplementation in MPTP-Intoxicated Mouse
por: Singh, Saumitra S., et al.
Publicado: (2018)

Corrigendum: Effect of chlorogenic acid supplementation in MPTP-intoxicated mouse
por: Singh, Saumitra S., et al.
Publicado: (2023)

Commentary: Mild endoplasmic reticulum stress ameliorates lpopolysaccharide-induced neuroinflammation and cognitive impairment via regulation of microglial polarization
por: Rai, Sachchida N., et al.
Publicado: (2018)

Economic Shock and Agri-Sector: Post-COVID-19 Scenario in India
por: Dilnashin, Hagera, et al.
Publicado: (2021)

Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson’s Disease through NF-κB/pAKT Signaling Pathways
por: Rai, Sachchida N., et al.
Publicado: (2017)

A Comparative Study of Effects of 28-Day Exposure of Bisphenol A and Bisphenol S on Body Weight Changes, Organ Histology, and Relative Organ Weight
por: Sharma, Parul, et al.
Publicado: (2021)

Molecular characterization, pathogen-host interaction pathway and in silico approaches for vaccine design against COVID-19
por: Singh, Nidhi, et al.
Publicado: (2020)

Metagenomic Analysis of Garden Soil-Derived Microbial Consortia and Unveiling Their Metabolic Potential in Mitigating Toxic Hexavalent Chromium
por: Singh, Nidhi, et al.
Publicado: (2022)

Flavonoids as Promising Neuroprotectants and Their Therapeutic Potential against Alzheimer's Disease
por: Minocha, Tarun, et al.
Publicado: (2022)

Commentary: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model
por: Rai, Sachchida Nand, et al.
Publicado: (2020)

Editorial: The role of mushrooms and their nutraceuticals for chronic and degenerative diseases
por: Rai, Sachchida Nand, et al.
Publicado: (2022)

Application of National Aerosol Facility (NAF) in Designing of a Ventilation System for Isolation Rooms to Minimize Interpersonal Exposure of Sneezing/Coughing
por: Singh, Ram Kumar, et al.
Publicado: (2020)

Role of Oxidative Stress and Metal Toxicity in the Progression of Alzheimer’s Disease
por: Birla, Hareram, et al.
Publicado: (2020)

Evaluation of Pleurotus Mushroom Effects on Histopathological Changes in Organs of Diabetic Rats
por: Dubey, Sushil Kumar, et al.
Publicado: (2023)

Demystifying the Role of Prognostic Biomarkers in Breast Cancer through Integrated Transcriptome and Pathway Enrichment Analyses
por: Mishra, Divya, et al.
Publicado: (2023)

Identification of Prognostic Biomarkers for Suppressing Tumorigenesis and Metastasis of Hepatocellular Carcinoma through Transcriptome Analysis
por: Mishra, Divya, et al.
Publicado: (2023)

Promising drug targets and associated therapeutic interventions in Parkinson’s disease
por: Rai, Sachchida Nand, et al.
Publicado: (2021)

The Role of Vitamins in Neurodegenerative Disease: An Update
por: Rai, Sachchida Nand, et al.
Publicado: (2021)

Therapeutic Potential of Vital Transcription Factors in Alzheimer’s and Parkinson’s Disease With Particular Emphasis on Transcription Factor EB Mediated Autophagy
por: Rai, Sachchida Nand, et al.
Publicado: (2021)

Rapid eco-friendly synthesis, characterization, and cytotoxic study of trimetallic stable nanomedicine: A potential material for biomedical applications
por: Chaturvedi, Vivek K., et al.
Publicado: (2020)

Expression, Purification, and In Silico Characterization of Mycobacterium smegmatis Alternative Sigma Factor SigB
por: Singh, Rakesh Kumar, et al.
Publicado: (2022)

Heavy Metal Contamination in the Aquatic Ecosystem: Toxicity and Its Remediation Using Eco-Friendly Approaches
por: Singh, Veer, et al.
Publicado: (2023)

Transcriptomic landscape of early age onset of colorectal cancer identifies novel genes and pathways in Indian CRC patients
por: Singh, Manish Pratap, et al.
Publicado: (2021)

Diagnosis of Genital Tuberculosis in Infertile Women by Using the Composite Reference Standard
por: Saxena, Riden, et al.
Publicado: (2022)

The Link between Obesity, Microbiota Dysbiosis, and Neurodegenerative Pathogenesis
por: Vamanu, Emanuel, et al.
Publicado: (2021)

Exploring the Paradox of COVID-19 in Neurological Complications with Emphasis on Parkinson's and Alzheimer's Disease
por: Rai, Sachchida Nand, et al.
Publicado: (2022)

Elevated Serum SIRT 2 May Differentiate Parkinson’s Disease From Atypical Parkinsonian Syndromes
por: Singh, Amrendra Pratap, et al.
Publicado: (2019)

Molecular subtypes of colorectal cancer: An emerging therapeutic opportunity for personalized medicine
por: Singh, Manish Pratap, et al.
Publicado: (2019)

Hexavalent-Chromium-Induced Oxidative Stress and the Protective Role of Antioxidants against Cellular Toxicity
por: Singh, Veer, et al.
Publicado: (2022)

Unsupervised machine learning-based clustering identifies unique molecular signatures of colorectal cancer with distinct clinical outcomes
por: Singh, Manish Pratap, et al.
Publicado: (2023)

Trojan Horse Delivery of 4,4′‐Dimethoxychalcone for Parkinsonian Neuroprotection
por: Zhang, Wenlong, et al.
Publicado: (2021)

Analgesic efficacy of dexamethasone versus dexmedetomidine as an adjuvant to ropivacaine in ultrasound-guided transversus abdominis plane block for post-operative pain relief in caesarean section: A prospective randomised controlled study
por: Singla, Nitika, et al.
Publicado: (2021)

Variations in Black Carbon concentration and sources during COVID-19 lockdown in Delhi
por: Goel, Vikas, et al.
Publicado: (2021)

Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices
por: Fernandes, Mara Yone D., et al.
Publicado: (2021)

Therapeutic Potential of Phytoconstituents in Management of Alzheimer's Disease
por: Singh, Anurag Kumar, et al.
Publicado: (2021)

WNT-β Catenin Signaling as a Potential Therapeutic Target for Neurodegenerative Diseases: Current Status and Future Perspective
por: Ramakrishna, Kakarla, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_p3sokulspbn4gs8qsh271pf8uj