Dysregulation of RNA-Binding Proteins in Amyotrophic Lateral Sclerosis

Genetic analyses of patients with amyotrophic lateral sclerosis (ALS) have revealed a strong association between mutations in genes encoding many RNA-binding proteins (RBPs), including TARDBP, FUS, hnRNPA1, hnRNPA2B1, MATR3, ATXN2, TAF15, TIA-1, and EWSR1, and disease onset/progression. RBPs are a g...

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Detalles Bibliográficos
Autores principales: Xue, Yuan Chao, Ng, Chen Seng, Xiang, Pinhao, Liu, Huitao, Zhang, Kevin, Mohamud, Yasir, Luo, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273501/
https://www.ncbi.nlm.nih.gov/pubmed/32547363
http://dx.doi.org/10.3389/fnmol.2020.00078

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