Role of fragile X mental retardation protein in chronic pain

Chronic pain has detrimental effects on one’s quality of life. However, its treatment options are very limited, and its underlying pathogenesis remains unclear. Recent research has suggested that fragile X mental retardation protein is involved in the development of chronic pain, making it a potenti...

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Autores principales: Mei, Xiangyang, Yang, Yixin, Zhao, Jinsong, Wang, Yongjie, Chen, QiLiang, Qian, Xiang, Li, Xiangyao, Feng, Zhiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273537/
https://www.ncbi.nlm.nih.gov/pubmed/32496847
http://dx.doi.org/10.1177/1744806920928619
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author Mei, Xiangyang
Yang, Yixin
Zhao, Jinsong
Wang, Yongjie
Chen, QiLiang
Qian, Xiang
Li, Xiangyao
Feng, Zhiying
author_facet Mei, Xiangyang
Yang, Yixin
Zhao, Jinsong
Wang, Yongjie
Chen, QiLiang
Qian, Xiang
Li, Xiangyao
Feng, Zhiying
author_sort Mei, Xiangyang
collection PubMed
description Chronic pain has detrimental effects on one’s quality of life. However, its treatment options are very limited, and its underlying pathogenesis remains unclear. Recent research has suggested that fragile X mental retardation protein is involved in the development of chronic pain, making it a potential target for prevention and treatment. The current review of literature will examine the function of fragile X mental retardation protein and its associated pathways, through which we hope to gain insight into how fragile X mental retardation protein may contribute to nociceptive sensitization and chronic pain.
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spelling pubmed-72735372020-06-15 Role of fragile X mental retardation protein in chronic pain Mei, Xiangyang Yang, Yixin Zhao, Jinsong Wang, Yongjie Chen, QiLiang Qian, Xiang Li, Xiangyao Feng, Zhiying Mol Pain Review Chronic pain has detrimental effects on one’s quality of life. However, its treatment options are very limited, and its underlying pathogenesis remains unclear. Recent research has suggested that fragile X mental retardation protein is involved in the development of chronic pain, making it a potential target for prevention and treatment. The current review of literature will examine the function of fragile X mental retardation protein and its associated pathways, through which we hope to gain insight into how fragile X mental retardation protein may contribute to nociceptive sensitization and chronic pain. SAGE Publications 2020-06-04 /pmc/articles/PMC7273537/ /pubmed/32496847 http://dx.doi.org/10.1177/1744806920928619 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Mei, Xiangyang
Yang, Yixin
Zhao, Jinsong
Wang, Yongjie
Chen, QiLiang
Qian, Xiang
Li, Xiangyao
Feng, Zhiying
Role of fragile X mental retardation protein in chronic pain
title Role of fragile X mental retardation protein in chronic pain
title_full Role of fragile X mental retardation protein in chronic pain
title_fullStr Role of fragile X mental retardation protein in chronic pain
title_full_unstemmed Role of fragile X mental retardation protein in chronic pain
title_short Role of fragile X mental retardation protein in chronic pain
title_sort role of fragile x mental retardation protein in chronic pain
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273537/
https://www.ncbi.nlm.nih.gov/pubmed/32496847
http://dx.doi.org/10.1177/1744806920928619
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