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Malnutrition and quality of life among adult inflammatory bowel disease patients

BACKGROUND AND AIM: Inflammatory bowel diseases (IBD) are chronic inflammatory conditions of the gut resulting in a significant risk for malnutrition. The reported prevalence of malnutrition in inflammatory disease patients varies from 5.7 to 82.8%. The aim of this study was to measure the prevalenc...

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Autores principales: Pulley, Jessica, Todd, Alwyn, Flatley, Christopher, Begun, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273715/
https://www.ncbi.nlm.nih.gov/pubmed/32514453
http://dx.doi.org/10.1002/jgh3.12278
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author Pulley, Jessica
Todd, Alwyn
Flatley, Christopher
Begun, Jakob
author_facet Pulley, Jessica
Todd, Alwyn
Flatley, Christopher
Begun, Jakob
author_sort Pulley, Jessica
collection PubMed
description BACKGROUND AND AIM: Inflammatory bowel diseases (IBD) are chronic inflammatory conditions of the gut resulting in a significant risk for malnutrition. The reported prevalence of malnutrition in inflammatory disease patients varies from 5.7 to 82.8%. The aim of this study was to measure the prevalence of malnutrition and its association with quality of life (QOL) in a cohort of Australian IBD outpatients. METHODS: A total of 107 consecutive patients (68 Crohn's disease, 35 ulcerative colitis, 4 indeterminate colitis) were enrolled in this cross‐sectional study. Demographic data were collected, and patients underwent a malnutrition assessment using the patient‐generated subjective global assessment. The RAND 36‐item health survey was used to measure QOL. RESULTS: Mild to moderate malnutrition was detected in 17 patients (16%). Malnourished patients were more likely to be underweight (P ≤ 0.01), have active disease (P ≤ 0.01), and have been admitted to hospital in the preceding 12 months (P ≤ 0.05). Malnourished patients had a significantly lower QOL in physical (P ≤ 0.01) and mental (P ≤ 0.01) health components. Patients with active or recently active disease had reduced QOL compared to patients in remission. Malnutrition factors predictive of poor physical health‐related QOL were pain (odds ratio [OR] = 12.8, 95% confidence interval [CI] 2.0–80.4) and unintentional weight loss (OR = 3.1 per kg lost, 95% CI 1.2–7.9). The predictor of poor mental health‐related QOL was early satiety (OR = 7.7, 95% CI 1.7–33.9). CONCLUSIONS: The malnutrition prevalence for this population was 16%. Malnutrition was associated with being underweight, active disease, and increased number of hospital admissions. Disease activity and malnutrition were associated with poorer QOL.
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spelling pubmed-72737152020-06-07 Malnutrition and quality of life among adult inflammatory bowel disease patients Pulley, Jessica Todd, Alwyn Flatley, Christopher Begun, Jakob JGH Open Original Articles BACKGROUND AND AIM: Inflammatory bowel diseases (IBD) are chronic inflammatory conditions of the gut resulting in a significant risk for malnutrition. The reported prevalence of malnutrition in inflammatory disease patients varies from 5.7 to 82.8%. The aim of this study was to measure the prevalence of malnutrition and its association with quality of life (QOL) in a cohort of Australian IBD outpatients. METHODS: A total of 107 consecutive patients (68 Crohn's disease, 35 ulcerative colitis, 4 indeterminate colitis) were enrolled in this cross‐sectional study. Demographic data were collected, and patients underwent a malnutrition assessment using the patient‐generated subjective global assessment. The RAND 36‐item health survey was used to measure QOL. RESULTS: Mild to moderate malnutrition was detected in 17 patients (16%). Malnourished patients were more likely to be underweight (P ≤ 0.01), have active disease (P ≤ 0.01), and have been admitted to hospital in the preceding 12 months (P ≤ 0.05). Malnourished patients had a significantly lower QOL in physical (P ≤ 0.01) and mental (P ≤ 0.01) health components. Patients with active or recently active disease had reduced QOL compared to patients in remission. Malnutrition factors predictive of poor physical health‐related QOL were pain (odds ratio [OR] = 12.8, 95% confidence interval [CI] 2.0–80.4) and unintentional weight loss (OR = 3.1 per kg lost, 95% CI 1.2–7.9). The predictor of poor mental health‐related QOL was early satiety (OR = 7.7, 95% CI 1.7–33.9). CONCLUSIONS: The malnutrition prevalence for this population was 16%. Malnutrition was associated with being underweight, active disease, and increased number of hospital admissions. Disease activity and malnutrition were associated with poorer QOL. Wiley Publishing Asia Pty Ltd 2019-11-14 /pmc/articles/PMC7273715/ /pubmed/32514453 http://dx.doi.org/10.1002/jgh3.12278 Text en © 2019 The Authors. JGH Open: An open access journal of gastroenterology and hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Pulley, Jessica
Todd, Alwyn
Flatley, Christopher
Begun, Jakob
Malnutrition and quality of life among adult inflammatory bowel disease patients
title Malnutrition and quality of life among adult inflammatory bowel disease patients
title_full Malnutrition and quality of life among adult inflammatory bowel disease patients
title_fullStr Malnutrition and quality of life among adult inflammatory bowel disease patients
title_full_unstemmed Malnutrition and quality of life among adult inflammatory bowel disease patients
title_short Malnutrition and quality of life among adult inflammatory bowel disease patients
title_sort malnutrition and quality of life among adult inflammatory bowel disease patients
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273715/
https://www.ncbi.nlm.nih.gov/pubmed/32514453
http://dx.doi.org/10.1002/jgh3.12278
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