Cargando…

The Metabolic Basis of Immune Dysfunction Following Sepsis and Trauma

Critically ill, severely injured and high-risk surgical patients are vulnerable to secondary infections during hospitalization and after hospital discharge. Studies show that the mitochondrial function and oxidative metabolism of monocytes and macrophages are impaired during sepsis. Alternatively, t...

Descripción completa

Detalles Bibliográficos
Autores principales:	McBride, Margaret A., Owen, Allison M., Stothers, Cody L., Hernandez, Antonio, Luan, Liming, Burelbach, Katherine R., Patil, Tazeen K., Bohannon, Julia K., Sherwood, Edward R., Patil, Naeem K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273750/ https://www.ncbi.nlm.nih.gov/pubmed/32547553 http://dx.doi.org/10.3389/fimmu.2020.01043

Ejemplares similares

MyD88-dependent signaling drives toll-like receptor-induced trained immunity in macrophages
por: Owen, Allison M., et al.
Publicado: (2022)

Immune Checkpoints: Novel Therapeutic Targets to Attenuate Sepsis-Induced Immunosuppression
por: McBride, Margaret A., et al.
Publicado: (2021)

Targeting Immune Cell Checkpoints during Sepsis
por: Patil, Naeem K., et al.
Publicado: (2017)

IL-15 Superagonist Expands mCD8(+ )T, NK and NKT Cells after Burn Injury but Fails to Improve Outcome during Burn Wound Infection
por: Patil, Naeem K., et al.
Publicado: (2016)

TLR Agonists as Mediators of Trained Immunity: Mechanistic Insight and Immunotherapeutic Potential to Combat Infection
por: Owen, Allison M., et al.
Publicado: (2021)

Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A
por: Luan, Liming, et al.
Publicado: (2017)

Editorial: The Roles of Mitochondria in Immunity
por: Patil, Naeem K., et al.
Publicado: (2022)

Loss of Sirtuin 1 (SIRT1) potentiates endothelial dysfunction via impaired glycolysis during infectious challenge
por: Stark, Ryan J., et al.
Publicado: (2022)

The role of natural killer cells in the pathogenesis of sepsis: the ongoing enigma
por: Bohannon, Julia, et al.
Publicado: (2012)

The role of CXCL10 in the pathogenesis of experimental septic shock
por: Herzig, Daniela S, et al.
Publicado: (2014)

Acute Abducens Nerve Palsy in a Patient who Sustained Mechanical Trauma to the Orbit
por: Geressu, Adam, et al.
Publicado: (2021)

The liver in sepsis: shedding light on the cellular basis of hepatocyte dysfunction
por: Marshall, John C
Publicado: (2013)

Editorial: Translational Insights Into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma
por: Radermacher, Peter, et al.
Publicado: (2020)

Gender differences in trauma, shock and sepsis
por: Bösch, Florian, et al.
Publicado: (2018)

Monitoring Detrusor Oxygenation and Hemodynamics Noninvasively during Dysfunctional Voiding
por: Macnab, Andrew J., et al.
Publicado: (2012)

Mystery of PCO(2) Gap in Sepsis
por: Patil, Vijaya P
Publicado: (2019)

Cohort profile: The Trauma Outcomes Project, a prospective study of New Zealanders experiencing major trauma
por: Owen, Helen E, et al.
Publicado: (2023)

Perspectives on the basis of seizure-induced respiratory dysfunction
por: Mulkey, Daniel K., et al.
Publicado: (2022)

The neural basis of spatial vision losses in the dysfunctional visual system
por: Huang, Jinfeng, et al.
Publicado: (2017)

Coxsackie Myocarditis with Severe Methicillin-resistant Staphylococcus aureus Sepsis, Multi-organ Dysfunction Syndrome, and Posterior Epidural Spinal Abscess: A Case Report
por: Morkar, Dnyanesh N, et al.
Publicado: (2020)

Multiple organ dysfunction after trauma
por: Cole, E., et al.
Publicado: (2019)

The behavioral and neural basis of empathic blame
por: Patil, Indrajeet, et al.
Publicado: (2017)

An Unrealistic Drift in Assay on Anhydrous Basis towards Content Limit
por: Shivram, K., et al.
Publicado: (2009)

Prediction of sepsis in trauma patients
por: Jin, He, et al.
Publicado: (2014)

Does Presence of Sepsis by Itself Predispose the Patients to HCAIs?
por: Gaikwad, Sheetal, et al.
Publicado: (2021)

Low expression of microRNA-328 can predict sepsis and alleviate sepsis-induced cardiac dysfunction and inflammatory response
por: Sun, Bin, et al.
Publicado: (2020)

Editorial: Community series in translational insights into mechanisms and therapy of organ dysfunction in sepsis and trauma, volume II
por: Relja, Borna, et al.
Publicado: (2023)

An integrative review of standardized clinical evaluation tool utilization in anticholinergic drug trials for neurogenic lower urinary tract dysfunction
por: Stothers, L, et al.
Publicado: (2016)

Vd/Vt test in the detection of pulmonary dysfunction in sepsis
por: Cala, K, et al.
Publicado: (2004)

Comparison of Injury Severity Score, New Injury Severity Score, Revised Trauma Score and Trauma and Injury Severity Score for Mortality Prediction in Elderly Trauma Patients
por: Javali, Rameshbabu Homanna, et al.
Publicado: (2019)

Lung ventilation strategies and regional lung inflammation
por: Luan, Liming, et al.
Publicado: (2013)

Neutrophil Dysfunction in Sepsis
por: Zhang, Fang, et al.
Publicado: (2016)

Ischemic Stroke in Confederation with Trivial Head Trauma
por: Balachandran, Archana, et al.
Publicado: (2016)

Renal Dysfunction in Prediabetes: Confirmed by Glomerular Hyperfiltration and Albuminuria
por: Shilpasree, Alagilawada S., et al.
Publicado: (2021)

Sepsis subphenotyping based on organ dysfunction trajectory
por: Xu, Zhenxing, et al.
Publicado: (2022)

Chronic muscle weakness and mitochondrial dysfunction in the absence of sustained atrophy in a preclinical sepsis model
por: Owen, Allison M, et al.
Publicado: (2019)

Comparison of the source and prognostic utility of cfDNA in trauma and sepsis
por: Jackson Chornenki, Nicholas L., et al.
Publicado: (2019)

The cellular basis of organ failure in sepsis—signaling during damage and repair processes
por: Bauer, M., et al.
Publicado: (2020)

Incidence and predictive risk factors of postoperative sepsis in orthopedic trauma patients
por: Lakomkin, Nikita, et al.
Publicado: (2016)

The neural basis of flashback formation: the impact of viewing trauma
por: Bourne, C., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_jgursp0kg8nq6v3vd6ohrjb48d