Plasma albumin levels predict risk for nonsurvivors in critically ill patients with COVID-19

Aim: We aimed to explore the biomarkers for disease progression or the risk of nonsurvivors. Materials & methods: This study included 134 hospitalized patients with confirmed COVID-19 infection. The outcome of moderate versus severe versus critically ill patients and survivors versus nonsurvivor...

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Detalles Bibliográficos
Autores principales: Li, Juyi, Li, Meng, Zheng, Shasha, Li, Menglan, Zhang, Minghua, Sun, Minxian, Li, Xiang, Deng, Aiping, Cai, Yi, Zhang, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273900/
https://www.ncbi.nlm.nih.gov/pubmed/32490680
http://dx.doi.org/10.2217/bmm-2020-0254
Descripción
Sumario:Aim: We aimed to explore the biomarkers for disease progression or the risk of nonsurvivors. Materials & methods: This study included 134 hospitalized patients with confirmed COVID-19 infection. The outcome of moderate versus severe versus critically ill patients and survivors versus nonsurvivors were compared. Results: An increase in the severity of COVID-19 pneumonia was positively associated with lower levels of platelets and albumin (all p < 0.05). In the critical group, the plasma levels of albumin continued to have a significant association for the risk of nonsurvivors (p < 0.05), even after adjusting for confounding factors. Conclusion: Albumin levels could be used as an independent predictor of the risk of nonsurvivors in critically ill patients with COVID-19.

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