Cargando…

Mechanism of N-acetylcysteine in alleviating diabetic myocardial ischemia reperfusion injury by regulating PTEN/Akt pathway through promoting DJ-1

Ischemic heart disease is the main cardiovascular complication of diabetes patients which is mainly caused by oxidative stress. DJ-1 is the key regulator for myocardial protection through inhibiting phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and activating Akt (also known as PKB...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wenyuan, Li, Wei, Leng, Yan, Xiong, Yonghong, Xue, Rui, Chen, Rong, Xia, Zhongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273917/
https://www.ncbi.nlm.nih.gov/pubmed/32347295
http://dx.doi.org/10.1042/BSR20192118