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Stimulation of GLP-1 Receptor Inhibits Methylglyoxal-Induced Mitochondrial Dysfunctions in H9c2 Cardiomyoblasts: Potential Role of Epac/PI3K/Akt Pathway

Accumulation of methylglyoxal (MG) contributes to oxidative stress, apoptosis, and mitochondrial dysfunction, leading to the development of type 2 diabetes and cardiovascular diseases. Inhibition of mitochondrial abnormalities induced by MG in the heart may improve and delay the progression of heart...

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Detalles Bibliográficos
Autores principales:	Nuamnaichati, Narawat, Mangmool, Supachoke, Chattipakorn, Nipon, Parichatikanond, Warisara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274035/ https://www.ncbi.nlm.nih.gov/pubmed/32547400 http://dx.doi.org/10.3389/fphar.2020.00805

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