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Rhein Derivative 4F Inhibits the Malignant Phenotype of Breast Cancer by Downregulating Rac1 Protein

BACKGROUND: Triple-negative breast cancer is a common malignant tumor with unfavorable prognosis affecting women worldwide; thus, there is an urgent need for novel therapeutic drugs with improved anti-tumor activity. Rac family small GTPase 1 (Rac1) plays an important role in malignant behavior and...

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Detalles Bibliográficos
Autores principales:	Li, Xinxiao, Liu, Yunfeng, Zhao, Yuhua, Tian, Wei, Zhai, Lina, Pang, Huifeng, Kang, Jiankang, Hou, Huaxin, Chen, Yanhua, Li, Danrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274043/ https://www.ncbi.nlm.nih.gov/pubmed/32547389 http://dx.doi.org/10.3389/fphar.2020.00754

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