Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function

COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory fun...

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Autores principales: Di Grezia, Marta, Fransvea, Pietro, Santullo, Francesco, Tirelli, Flavio, Fico, Valeria, Mirco, Paolo, Cozza, Valerio, La Greca, Antonio, Sganga, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274106/
https://www.ncbi.nlm.nih.gov/pubmed/32531539
http://dx.doi.org/10.1016/j.mehy.2020.109954
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author Di Grezia, Marta
Fransvea, Pietro
Santullo, Francesco
Tirelli, Flavio
Fico, Valeria
Mirco, Paolo
Cozza, Valerio
La Greca, Antonio
Sganga, Gabriele
author_facet Di Grezia, Marta
Fransvea, Pietro
Santullo, Francesco
Tirelli, Flavio
Fico, Valeria
Mirco, Paolo
Cozza, Valerio
La Greca, Antonio
Sganga, Gabriele
author_sort Di Grezia, Marta
collection PubMed
description COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function.
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spelling pubmed-72741062020-06-05 Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function Di Grezia, Marta Fransvea, Pietro Santullo, Francesco Tirelli, Flavio Fico, Valeria Mirco, Paolo Cozza, Valerio La Greca, Antonio Sganga, Gabriele Med Hypotheses Article COVID-19 gastrointestinal manifestations could be attributed to SARS-CoV-2-induced small vessel thrombosis. OA with NPT treatment may have a role in optimization of bowel microcirculation and in the reduction of the endothelial and the systemic cytokine-related damage, improving also respiratory function. Elsevier Ltd. 2020-11 2020-06-05 /pmc/articles/PMC7274106/ /pubmed/32531539 http://dx.doi.org/10.1016/j.mehy.2020.109954 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Di Grezia, Marta
Fransvea, Pietro
Santullo, Francesco
Tirelli, Flavio
Fico, Valeria
Mirco, Paolo
Cozza, Valerio
La Greca, Antonio
Sganga, Gabriele
Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function
title Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function
title_full Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function
title_fullStr Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function
title_full_unstemmed Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function
title_short Intra-abdominal hypertension as a trigger of “gut failure” in SARS-CoV-2 infection: Effect of open abdomen (OA) and negative pressure therapy (NPT) on respiratory and gastrointestinal (GI) function
title_sort intra-abdominal hypertension as a trigger of “gut failure” in sars-cov-2 infection: effect of open abdomen (oa) and negative pressure therapy (npt) on respiratory and gastrointestinal (gi) function
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274106/
https://www.ncbi.nlm.nih.gov/pubmed/32531539
http://dx.doi.org/10.1016/j.mehy.2020.109954
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