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Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis

In response to various stimuli, vascular smooth muscle cells (SMCs) can de-differentiate, proliferate and migrate in a process known as phenotypic modulation. However, the phenotype of modulated SMCs in vivo during atherosclerosis and the influence of this process on coronary artery disease (CAD) ri...

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Detalles Bibliográficos
Autores principales: Wirka, Robert C., Wagh, Dhananjay, Paik, David T., Pjanic, Milos, Nguyen, Trieu, Miller, Clint L., Kundu, Ramen, Nagao, Manabu, Coller, John, Koyano, Tiffany K., Fong, Robyn, Woo, Y. Joseph, Liu, Boxiang, Montgomery, Stephen B., Wu, Joseph C., Zhu, Kuixi, Chang, Rui, Alamprese, Melissa, Tallquist, Michelle D., Kim, Juyong B., Quertermous, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274198/
https://www.ncbi.nlm.nih.gov/pubmed/31359001
http://dx.doi.org/10.1038/s41591-019-0512-5

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