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Effects of castration on atherosclerosis in Yucatan minipigs with genetic hypercholesterolemia
BACKGROUND: Low plasma testosterone, either spontaneous or as a result of androgen deprivation therapy for prostate cancer, is associated with an increased risk of cardiovascular events. The underlying mechanism in humans is not understood. Experimental studies in mice have shown that castration fac...
Autores principales: | Shim, Jeong T., Schmidt, Nikolaj, Nogales, Paula, Larsen, Torben, Sørensen, Charlotte B., Bentzon, Jacob F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274396/ https://www.ncbi.nlm.nih.gov/pubmed/32502216 http://dx.doi.org/10.1371/journal.pone.0234131 |
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