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Ultra-sensitive detection of Mycobacterium leprae: DNA extraction and PCR assays
Leprosy urgently needs a precise and early diagnostic tool. The sensitivity of the direct (bacilli staining, Mycobacterium leprae DNA) and indirect (antibody levels, T cell assays) diagnostics methods vary based on the clinical form. Recently, PCR-based M. leprae DNA detection has been shown to diff...
Autores principales: | Manta, Fernanda Saloum de Neves, Leal-Calvo, Thyago, Moreira, Suelen Justo M., Marques, Brunna L. C., Ribeiro-Alves, Marcelo, Rosa, Patrícia S., Nery, José Augusto C., Rampazzo, Rita de Cássia Pontello, Costa, Alexandre Dias Tavares, Krieger, Marco Aurelio, Moraes, Milton Ozório |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274454/ https://www.ncbi.nlm.nih.gov/pubmed/32453754 http://dx.doi.org/10.1371/journal.pntd.0008325 |
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