Cargando…

Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone

Hormone-dependent activation of enhancers includes histone hyperacetylation and mediator recruitment. Histone hyperacetylation is mostly explained by a bimodal switch model, where histone deacetylases (HDACs) disassociate from chromatin, and histone acetyl transferases (HATs) are recruited. This mod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Præstholm, Stine M., Siersbæk, Majken S., Nielsen, Ronni, Zhu, Xuguang, Hollenberg, Anthony N., Cheng, Sheue-yann, Grøntved, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274477/ https://www.ncbi.nlm.nih.gov/pubmed/32453730 http://dx.doi.org/10.1371/journal.pgen.1008770

Ejemplares similares

Insulin signaling and reduced glucocorticoid receptor activity attenuate postprandial gene expression in liver
por: Kalvisa, Adrija, et al.
Publicado: (2018)

High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss
por: Siersbæk, Majken, et al.
Publicado: (2017)

Multifaceted Control of GR Signaling and Its Impact on Hepatic Transcriptional Networks and Metabolism
por: Præstholm, Stine M., et al.
Publicado: (2020)

Genetic and Pharmacological Targeting of Transcriptional Repression in Resistance to Thyroid Hormone Alpha
por: Freudenthal, Bernard, et al.
Publicado: (2019)

Synergistic Signaling of KRAS and Thyroid Hormone Receptor β Mutants Promotes Undifferentiated Thyroid Cancer through MYC Up-Regulation()()
por: Zhu, Xuguang, et al.
Publicado: (2014)

Epigenetic Modifications: Novel Therapeutic Approach for Thyroid Cancer
por: Zhu, Xuguang, et al.
Publicado: (2017)

C57BL/6J substrain differences in response to high-fat diet intervention
por: Siersbæk, Majken Storm, et al.
Publicado: (2020)

Defective erythropoiesis caused by mutations of the thyroid hormone receptor α gene
por: Park, Sunmi, et al.
Publicado: (2017)

Oncogenic mutations of thyroid hormone receptor β
por: Park, Jeong Won, et al.
Publicado: (2015)

NCOR1 modulates erythroid disorders caused by mutations of thyroid hormone receptor α1
por: Han, Cho Rong, et al.
Publicado: (2017)

Thyroid Hormone Receptor α Mutation Causes a Severe and Thyroxine-Resistant Skeletal Dysplasia in Female Mice
por: Bassett, J. H. Duncan, et al.
Publicado: (2014)

Synergistic effects of BET and MEK inhibitors promote regression of anaplastic thyroid tumors
por: Zhu, Xuguang, et al.
Publicado: (2018)

Src-dependent phosphorylation at Y406 on the thyroid hormone receptor β confers the tumor suppressor activity
por: Park, Jeong Won, et al.
Publicado: (2014)

Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance
por: Miller, Lance D, et al.
Publicado: (2004)

SAT-560 Role of COUP-TFII and Thyroid Hormone Receptor α in Skeletal Muscle Loss
por: Aguiari, Paola, et al.
Publicado: (2019)

Analysis of Hypothalamic TRH Neurons in Regulating Thyroid Hormone Levels
por: Costa e Sousa, Ricardo H, et al.
Publicado: (2021)

Targeting transcriptional regulators for treatment of anaplastic thyroid cancer
por: Lee, Woo Kyung, et al.
Publicado: (2021)

Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha
por: Aguiari, Paola, et al.
Publicado: (2021)

Persistent COUP-TFII Expression Underlies the Myopathy and Impaired Muscle Regeneration Observed in Resistance to Thyroid Hormone-Alpha
por: Aguiari, Paola, et al.
Publicado: (2021)

SUN-338 Inflammation Promotes Aggressive Thyroid Cancer Progression in a Mouse Model
por: Park, Sunmi, et al.
Publicado: (2019)

Tumor Cells and Cancer-Associated Fibroblasts: A Synergistic Crosstalk to Promote Thyroid Cancer
por: Fozzatti, Laura, et al.
Publicado: (2020)

Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial
por: Godskesen, Line E., et al.
Publicado: (2020)

Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells
por: Weis-Banke, Stine Emilie, et al.
Publicado: (2022)

Editorial: Translational research in thyroid cancer, Volume II
por: Cheng, Sheue-yann, et al.
Publicado: (2023)

MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3
por: Hallenborg, P, et al.
Publicado: (2016)

Editorial: Translational Research in Thyroid Cancer
por: Vasko, Vasyl, et al.
Publicado: (2020)

Loss of Primary Cilia Results in the Development of Cancer in the Murine Thyroid Gland
por: Lee, Junguee, et al.
Publicado: (2019)

Thyroid Stimulating Hormone Triggers Hepatic Mitochondrial Stress through Cyclophilin D Acetylation
por: Wang, Xiaolei, et al.
Publicado: (2020)

TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer
por: Perez-Penco, Maria, et al.
Publicado: (2022)

iPSC-Derived Human Hepatocytes as a Novel Model to Investigate Thyroid Hormone Action and Signaling
por: De Oliveira, Lorraine Soares, et al.
Publicado: (2021)

Cell non-autonomous effect of hepatic growth differentiation factor 15 on the thyroid gland
por: Jeong, Seonhyang, et al.
Publicado: (2022)

Associations between Recreational and Commuter Cycling, Changes in Cycling, and Type 2 Diabetes Risk: A Cohort Study of Danish Men and Women
por: Rasmussen, Martin G., et al.
Publicado: (2016)

Collagen density regulates the activity of tumor-infiltrating T cells
por: Kuczek, Dorota E., et al.
Publicado: (2019)

Acetylated histone H4 tail enhances histone H3 tail acetylation by altering their mutual dynamics in the nucleosome
por: Furukawa, Ayako, et al.
Publicado: (2020)

Histone Deacetylase Inhibitors Globally Enhance H3/H4 Tail Acetylation Without Affecting H3 Lysine 56 Acetylation
por: Drogaris, Paul, et al.
Publicado: (2012)

Metformin blocks progression of obesity-activated thyroid cancer in a mouse model
por: Park, Jeongwon, et al.
Publicado: (2016)

Oncogenic Actions of the Nuclear Receptor Corepressor (NCOR1) in a Mouse Model of Thyroid Cancer
por: Fozzatti, Laura, et al.
Publicado: (2013)

Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers
por: Loft, Anne, et al.
Publicado: (2015)

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action
por: Shimizu, Hiroaki, et al.
Publicado: (2019)

Interplay between TRα1 and Wnt signaling: A dangerous liaison
por: Cheng, Sheue-Yann
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_s333c0s21lh4b22q130k47fvhu