How to perform a nasopharyngeal swab in adults and children in the COVID-19 era

The nasopharyngeal swab is currently the main testing method used to diagnose COVID-19. The principle is to collect respiratory cells infected by the virus and to use the RT-PCR (Reverse Transcription - Polymerase Chain Reaction) technique to detect the RNA of the virus. The false negative rate is h...

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Detalles Bibliográficos
Autores principales: Pondaven-Letourmy, S., Alvin, F., Boumghit, Y., Simon, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274641/
https://www.ncbi.nlm.nih.gov/pubmed/32646750
http://dx.doi.org/10.1016/j.anorl.2020.06.001
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author Pondaven-Letourmy, S.
Alvin, F.
Boumghit, Y.
Simon, F.
author_facet Pondaven-Letourmy, S.
Alvin, F.
Boumghit, Y.
Simon, F.
author_sort Pondaven-Letourmy, S.
collection PubMed
description The nasopharyngeal swab is currently the main testing method used to diagnose COVID-19. The principle is to collect respiratory cells infected by the virus and to use the RT-PCR (Reverse Transcription - Polymerase Chain Reaction) technique to detect the RNA of the virus. The false negative rate is high, about 30%, which can mainly be explained by an incorrect execution of the technique may increase the false negative rate and decrease the test's sensitivity. The aim of this note is to help healthcare providers to perform this test correctly in adults and children.
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spelling pubmed-72746412020-06-08 How to perform a nasopharyngeal swab in adults and children in the COVID-19 era Pondaven-Letourmy, S. Alvin, F. Boumghit, Y. Simon, F. Eur Ann Otorhinolaryngol Head Neck Dis Article The nasopharyngeal swab is currently the main testing method used to diagnose COVID-19. The principle is to collect respiratory cells infected by the virus and to use the RT-PCR (Reverse Transcription - Polymerase Chain Reaction) technique to detect the RNA of the virus. The false negative rate is high, about 30%, which can mainly be explained by an incorrect execution of the technique may increase the false negative rate and decrease the test's sensitivity. The aim of this note is to help healthcare providers to perform this test correctly in adults and children. Elsevier Masson SAS. 2020-09 2020-06-05 /pmc/articles/PMC7274641/ /pubmed/32646750 http://dx.doi.org/10.1016/j.anorl.2020.06.001 Text en © 2020 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Pondaven-Letourmy, S.
Alvin, F.
Boumghit, Y.
Simon, F.
How to perform a nasopharyngeal swab in adults and children in the COVID-19 era
title How to perform a nasopharyngeal swab in adults and children in the COVID-19 era
title_full How to perform a nasopharyngeal swab in adults and children in the COVID-19 era
title_fullStr How to perform a nasopharyngeal swab in adults and children in the COVID-19 era
title_full_unstemmed How to perform a nasopharyngeal swab in adults and children in the COVID-19 era
title_short How to perform a nasopharyngeal swab in adults and children in the COVID-19 era
title_sort how to perform a nasopharyngeal swab in adults and children in the covid-19 era
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274641/
https://www.ncbi.nlm.nih.gov/pubmed/32646750
http://dx.doi.org/10.1016/j.anorl.2020.06.001
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