Human interleukin-4–treated regulatory macrophages promote epithelial wound healing and reduce colitis in a mouse model

Murine alternatively activated macrophages can exert anti-inflammatory effects. We sought to determine if IL-4–treated human macrophages [i.e., hM(IL4)] would promote epithelial wound repair and can serve as a cell transfer treatment for inflammatory bowel disease (IBD). Blood monocytes from healthy...

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Detalles Bibliográficos
Autores principales: Jayme, Timothy S., Leung, Gabriella, Wang, Arthur, Workentine, Matthew L., Rajeev, Sruthi, Shute, Adam, Callejas, Blanca E., Mancini, Nicole, Beck, Paul L., Panaccione, Remo, McKay, Derek M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274799/
https://www.ncbi.nlm.nih.gov/pubmed/32548267
http://dx.doi.org/10.1126/sciadv.aba4376

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