Cargando…
Meta-analysis of drug efficacy in adult vs pediatric trials of patients with PGTC seizures
OBJECTIVE: A meta-analysis of published studies was performed to determine whether the efficacy of antiseizure drugs in adults with primary generalized tonic-clonic seizures (PGTCS) is comparable with that in the pediatric population (2–12 years of age). METHODS: Electronic searches were conducted i...
Autores principales: | Nordli, Douglas R., Bagiella, Emilia, Arzimanoglou, Alexis, Wang, Jinping, Kumar, Dinesh, Laurenza, Antonio, French, Jacqueline |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274844/ https://www.ncbi.nlm.nih.gov/pubmed/32238509 http://dx.doi.org/10.1212/WNL.0000000000009325 |
Ejemplares similares
-
Novel study design to assess the efficacy and tolerability of antiseizure medications for focal‐onset seizures in infants and young children: A consensus document from the regulatory task force and the pediatric commission of the International League against Epilepsy (ILAE), in collaboration with the Pediatric Epilepsy Research Consortium (PERC)
por: Auvin, Stéphane, et al.
Publicado: (2019) -
Open‐label study to investigate the safety and efficacy of adjunctive perampanel in pediatric patients (4 to <12 years) with inadequately controlled focal seizures or generalized tonic‐clonic seizures
por: Fogarasi, Andras, et al.
Publicado: (2020) -
Perampanel efficacy and safety by gender: Subanalysis of phase III randomized clinical studies in subjects with partial seizures
por: Vazquez, Blanca, et al.
Publicado: (2015) -
Greater Response to Placebo in Children Than in Adults: A Systematic Review and Meta-Analysis in Drug-Resistant Partial Epilepsy
por: Rheims, Sylvain, et al.
Publicado: (2008) -
Cognitive effects of adjunctive perampanel for partial‐onset seizures: A randomized trial
por: Meador, Kimford J., et al.
Publicado: (2016)