m(5)C modification of mRNA serves a DNA damage code to promote homologous recombination

Recruitment of DNA repair proteins to DNA damage sites is a critical step for DNA repair. Post-translational modifications of proteins at DNA damage sites serve as DNA damage codes to recruit specific DNA repair factors. Here, we show that mRNA is locally modified by m(5)C at sites of DNA damage. Th...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Yang, Haibo, Zhu, Xiaolan, Yadav, Tribhuwan, Ouyang, Jian, Truesdell, Samuel S., Tan, Jun, Wang, Yumin, Duan, Meihan, Wei, Leizhen, Zou, Lee, Levine, Arthur S., Vasudevan, Shobha, Lan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275041/
https://www.ncbi.nlm.nih.gov/pubmed/32503981
http://dx.doi.org/10.1038/s41467-020-16722-7

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