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Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica

Type I interferon (IFN-I) and T helper 17 (TH17) drive pathology in neuromyelitis optica spectrum disorder (NMOSD) and in TH17-induced experimental autoimmune encephalomyelitis (TH17-EAE). This is paradoxical because the prevalent theory is that IFN-I inhibits TH17 function. Here we report that a ca...

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Detalles Bibliográficos
Autores principales:	Agasing, Agnieshka M., Wu, Qi, Khatri, Bhuwan, Borisow, Nadja, Ruprecht, Klemens, Brandt, Alexander Ulrich, Gawde, Saurabh, Kumar, Gaurav, Quinn, James L., Ko, Rose M., Mao-Draayer, Yang, Lessard, Christopher J., Paul, Friedemann, Axtell, Robert C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275086/ https://www.ncbi.nlm.nih.gov/pubmed/32503977 http://dx.doi.org/10.1038/s41467-020-16625-7

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