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Mode of action of teixobactins in cellular membranes

The natural antibiotic teixobactin kills pathogenic bacteria without detectable resistance. The difficult synthesis and unfavourable solubility of teixobactin require modifications, yet insufficient knowledge on its binding mode impedes the hunt for superior analogues. Thus far, teixobactins are ass...

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Detalles Bibliográficos
Autores principales:	Shukla, Rhythm, Medeiros-Silva, João, Parmar, Anish, Vermeulen, Bram J. A., Das, Sanjit, Paioni, Alessandra Lucini, Jekhmane, Shehrazade, Lorent, Joseph, Bonvin, Alexandre M. J. J., Baldus, Marc, Lelli, Moreno, Veldhuizen, Edwin J. A., Breukink, Eefjan, Singh, Ishwar, Weingarth, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275090/ https://www.ncbi.nlm.nih.gov/pubmed/32503964 http://dx.doi.org/10.1038/s41467-020-16600-2

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