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Time From HIV Diagnosis to Viral Suppression: Survival Analysis of Statewide Surveillance Data in Alabama, 2012 to 2014

BACKGROUND: Evaluation of the time from HIV diagnosis to viral suppression (VS) captures the collective effectiveness of HIV prevention and treatment activities in a given locale and provides a more global estimate of how effectively the larger HIV care system is working in a given geographic area o...

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Autores principales: Batey, D Scott, Dong, Xueyuan, Rogers, Richard P, Merriweather, Anthony, Elopre, Latesha, Rana, Aadia I, Hall, H Irene, Mugavero, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275256/
https://www.ncbi.nlm.nih.gov/pubmed/32045344
http://dx.doi.org/10.2196/17217
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author Batey, D Scott
Dong, Xueyuan
Rogers, Richard P
Merriweather, Anthony
Elopre, Latesha
Rana, Aadia I
Hall, H Irene
Mugavero, Michael J
author_facet Batey, D Scott
Dong, Xueyuan
Rogers, Richard P
Merriweather, Anthony
Elopre, Latesha
Rana, Aadia I
Hall, H Irene
Mugavero, Michael J
author_sort Batey, D Scott
collection PubMed
description BACKGROUND: Evaluation of the time from HIV diagnosis to viral suppression (VS) captures the collective effectiveness of HIV prevention and treatment activities in a given locale and provides a more global estimate of how effectively the larger HIV care system is working in a given geographic area or jurisdiction. OBJECTIVE: This study aimed to evaluate temporal and geographic variability in VS among persons with newly diagnosed HIV infection in Alabama between 2012 and 2014. METHODS: With data from the National HIV Surveillance System, we evaluated median time from HIV diagnosis to VS (<200 c/mL) overall and stratified by Alabama public health area (PHA) among persons with HIV diagnosed during 2012 to 2014 using the Kaplan-Meier approach. RESULTS: Among 1979 newly diagnosed persons, 1181 (59.67%) achieved VS within 12 months of diagnosis; 52.6% (353/671) in 2012, 59.5% (377/634) in 2013, and 66.9% (451/674) in 2014. Median time from HIV diagnosis to VS was 8 months: 10 months in 2012, 8 months in 2013, and 6 months in 2014. Across 11 PHAs in Alabama, 12-month VS ranged from 45.8% (130/284) to 84% (26/31), and median time from diagnosis to VS ranged from 5 to 13 months. CONCLUSIONS: Temporal improvement in persons achieving VS following HIV diagnosis statewide in Alabama is encouraging. However, considerable geographic variability warrants further evaluation to inform public health action. Time from HIV diagnosis to VS represents a meaningful indicator that can be incorporated into public health surveillance and programming.
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spelling pubmed-72752562020-06-16 Time From HIV Diagnosis to Viral Suppression: Survival Analysis of Statewide Surveillance Data in Alabama, 2012 to 2014 Batey, D Scott Dong, Xueyuan Rogers, Richard P Merriweather, Anthony Elopre, Latesha Rana, Aadia I Hall, H Irene Mugavero, Michael J JMIR Public Health Surveill Original Paper BACKGROUND: Evaluation of the time from HIV diagnosis to viral suppression (VS) captures the collective effectiveness of HIV prevention and treatment activities in a given locale and provides a more global estimate of how effectively the larger HIV care system is working in a given geographic area or jurisdiction. OBJECTIVE: This study aimed to evaluate temporal and geographic variability in VS among persons with newly diagnosed HIV infection in Alabama between 2012 and 2014. METHODS: With data from the National HIV Surveillance System, we evaluated median time from HIV diagnosis to VS (<200 c/mL) overall and stratified by Alabama public health area (PHA) among persons with HIV diagnosed during 2012 to 2014 using the Kaplan-Meier approach. RESULTS: Among 1979 newly diagnosed persons, 1181 (59.67%) achieved VS within 12 months of diagnosis; 52.6% (353/671) in 2012, 59.5% (377/634) in 2013, and 66.9% (451/674) in 2014. Median time from HIV diagnosis to VS was 8 months: 10 months in 2012, 8 months in 2013, and 6 months in 2014. Across 11 PHAs in Alabama, 12-month VS ranged from 45.8% (130/284) to 84% (26/31), and median time from diagnosis to VS ranged from 5 to 13 months. CONCLUSIONS: Temporal improvement in persons achieving VS following HIV diagnosis statewide in Alabama is encouraging. However, considerable geographic variability warrants further evaluation to inform public health action. Time from HIV diagnosis to VS represents a meaningful indicator that can be incorporated into public health surveillance and programming. JMIR Publications 2020-05-22 /pmc/articles/PMC7275256/ /pubmed/32045344 http://dx.doi.org/10.2196/17217 Text en ©D Scott Batey, Xueyuan Dong, Richard P Rogers, Anthony Merriweather, Latesha Elopre, Aadia I Rana, H Irene Hall, Michael J Mugavero. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 22.05.2020. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Public Health and Surveillance, is properly cited. The complete bibliographic information, a link to the original publication on http://publichealth.jmir.org, as well as this copyright and license information must be included.
spellingShingle Original Paper
Batey, D Scott
Dong, Xueyuan
Rogers, Richard P
Merriweather, Anthony
Elopre, Latesha
Rana, Aadia I
Hall, H Irene
Mugavero, Michael J
Time From HIV Diagnosis to Viral Suppression: Survival Analysis of Statewide Surveillance Data in Alabama, 2012 to 2014
title Time From HIV Diagnosis to Viral Suppression: Survival Analysis of Statewide Surveillance Data in Alabama, 2012 to 2014
title_full Time From HIV Diagnosis to Viral Suppression: Survival Analysis of Statewide Surveillance Data in Alabama, 2012 to 2014
title_fullStr Time From HIV Diagnosis to Viral Suppression: Survival Analysis of Statewide Surveillance Data in Alabama, 2012 to 2014
title_full_unstemmed Time From HIV Diagnosis to Viral Suppression: Survival Analysis of Statewide Surveillance Data in Alabama, 2012 to 2014
title_short Time From HIV Diagnosis to Viral Suppression: Survival Analysis of Statewide Surveillance Data in Alabama, 2012 to 2014
title_sort time from hiv diagnosis to viral suppression: survival analysis of statewide surveillance data in alabama, 2012 to 2014
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275256/
https://www.ncbi.nlm.nih.gov/pubmed/32045344
http://dx.doi.org/10.2196/17217
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