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Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase

BACKGROUND: Effectiveness of L-asparaginase administration in acute lymphoblastic leukemia treatment is mirrored in the overall outcome of patients. Generally, leukemia patients differ in their sensitivity to L-asparaginase; however, the mechanism underlying their inter-individual differences is sti...

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Detalles Bibliográficos
Autores principales:	Hlozkova, Katerina, Pecinova, Alena, Alquezar-Artieda, Natividad, Pajuelo-Reguera, David, Simcikova, Marketa, Hovorkova, Lenka, Rejlova, Katerina, Zaliova, Marketa, Mracek, Tomas, Kolenova, Alexandra, Stary, Jan, Trka, Jan, Starkova, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275298/ https://www.ncbi.nlm.nih.gov/pubmed/32503472 http://dx.doi.org/10.1186/s12885-020-07020-y

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