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Harnessing regulatory T cell neuroprotective activities for treatment of neurodegenerative disorders
ABSTRACT: Emerging evidence demonstrates that adaptive immunity influences the pathobiology of neurodegenerative disorders. Misfolded aggregated self-proteins can break immune tolerance leading to the induction of autoreactive effector T cells (Teffs) with associated decreases in anti-inflammatory n...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275301/ https://www.ncbi.nlm.nih.gov/pubmed/32503641 http://dx.doi.org/10.1186/s13024-020-00375-7 |