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Prevalence of mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, and association with ex vivo susceptibility to common anti-malarial drugs against African Plasmodium falciparum isolates

BACKGROUND: The Plasmodium falciparum chloroquine transporter gene (pfcrt) is known to be involved in chloroquine and amodiaquine resistance, and more particularly the mutations on the loci 72 to 76 localized within the second exon. Additionally, new mutations (T93S, H97Y, C101F, F145I, M343L, C350R...

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Detalles Bibliográficos
Autores principales:	Foguim, Francis Tsombeng, Bogreau, Hervé, Gendrot, Mathieu, Mosnier, Joel, Fonta, Isabelle, Benoit, Nicolas, Amalvict, Rémy, Madamet, Marylin, Wein, Sharon, Pradines, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275453/ https://www.ncbi.nlm.nih.gov/pubmed/32503540 http://dx.doi.org/10.1186/s12936-020-03281-x

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