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Immunopathology in schistosomiasis is regulated by TLR2,4- and IFN-γ-activated MSC through modulating Th1/Th2 responses

BACKGROUND AND AIMS: A marked egg-induced CD4(+) T cell programmed inflammation and subsequent hepatic fibrosis characterize the pathogenesis of schistosomiasis. Mesenchymal stem cell (MSC) has been extensively studied for the treatment of schistosomiasis. However, the mechanism by which MSCs modula...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Zhang, Yi-shu, Chen, Fang, Wu, Xiao-ying, Zhang, Bei-bei, Wu, Zhong-dao, Lei, Jun-xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275460/
https://www.ncbi.nlm.nih.gov/pubmed/32503644
http://dx.doi.org/10.1186/s13287-020-01735-2