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β1 adrenoceptor antibodies induce myocardial apoptosis via inhibiting PGC-1α-related pathway

BACKGROUND: Peripartum cardiomyopathy (PPCM) is life-threatening heart disease. However, the causes and pathogenesis of PPCM remain unclear. Previous studies found that β1 adrenoceptor antibodies (β1AA) had possible involvement in the development of PPCM. In the present study, we determined the pote...

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Detalles Bibliográficos
Autores principales: Shi, Linying, Liu, Jia, Zhang, Yuan, Chen, Mulei, Liu, Jiamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275518/
https://www.ncbi.nlm.nih.gov/pubmed/32503464
http://dx.doi.org/10.1186/s12872-020-01492-3