Liquid–liquid phase separation of type II diabetes-associated IAPP initiates hydrogelation and aggregation

Amyloidoses (misfolded polypeptide accumulation) are among the most debilitating diseases our aging societies face. Amyloidogenesis can be catalyzed by hydrophobic–hydrophilic interfaces (e.g., air–water interface in vitro [AWI]). We recently demonstrated hydrogelation of the amyloidogenic type II d...

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Detalles Bibliográficos
Autores principales: Pytowski, Lior, Lee, Chiu Fan, Foley, Alex C., Vaux, David J., Jean, Létitia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275713/
https://www.ncbi.nlm.nih.gov/pubmed/32414928
http://dx.doi.org/10.1073/pnas.1916716117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275713/
https://www.ncbi.nlm.nih.gov/pubmed/32414928
http://dx.doi.org/10.1073/pnas.1916716117

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