CXCL5-mediated recruitment of neutrophils into the peritoneal cavity of Gdf15-deficient mice protects against abdominal sepsis

Sepsis is a life-threatening organ dysfunction condition caused by a dysregulated host response to an infection. Here we report that the circulating levels of growth and differentiation factor-15 (GDF15) are strongly increased in septic shock patients and correlate with mortality. In mice, we find t...

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Detalles Bibliográficos
Autores principales: Santos, Isa, Colaço, Henrique G., Neves-Costa, Ana, Seixas, Elsa, Velho, Tiago R., Pedroso, Dora, Barros, André, Martins, Rui, Carvalho, Nuno, Payen, Didier, Weis, Sebastian, Yi, Hyon-Seung, Shong, Minho, Moita, Luís F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275717/
https://www.ncbi.nlm.nih.gov/pubmed/32424099
http://dx.doi.org/10.1073/pnas.1918508117

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