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HSP90 overexpression potentiates the B-cell receptor and fibroblast growth factor receptor survival signals in chronic lymphocytic leukemia cells
Chronic lymphocytic leukemia (CLL) is still an incurable disease despite aggressive chemotherapies including the B-cell receptor (BCR) targeted-inhibitors. Therefore, we assessed the expression status of key signal mediators of the BCR pathway in CLL cells. Indeed, we detected aberrantly elevated le...
Autores principales: | Mahmud, Hasan, Mendez, Mariana, Mukhopadhyay, Bedabrata, Holter-Chakrabarty, Jennifer, Ghosh, Asish K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275782/ https://www.ncbi.nlm.nih.gov/pubmed/32547702 http://dx.doi.org/10.18632/oncotarget.27409 |
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