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Transposon vector-mediated stable gene transfer for the accelerated establishment of recombinant mammalian cell pools allowing for high-yield production of biologics

Stable recombinant mammalian cells are of growing importance in pharmaceutical biotechnology production scenarios for biologics such as monoclonal antibodies, growth and blood factors, cytokines and subunit vaccines. However, the establishment of recombinant producer cells using classical stable tra...

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Detalles Bibliográficos
Autores principales: Tschorn, Natalie, Berg, Karen, Stitz, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275939/
https://www.ncbi.nlm.nih.gov/pubmed/32323079
http://dx.doi.org/10.1007/s10529-020-02889-y

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