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Homegrown Ultraviolet Germicidal Irradiation for Hospital-Based N95 Decontamination during the COVID-19 Pandemic
Coronavirus disease (COVID-19), the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, is responsible for the 2020 global pandemic and characterized by high transmissibility and morbidity. Healthcare workers (HCWs) are at risk of contracting COVID-19, and this...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276019/ https://www.ncbi.nlm.nih.gov/pubmed/32511592 http://dx.doi.org/10.1101/2020.04.29.20085456 |
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author | Schnell, Eric Harriff, Melanie J. Yates, Jane E. Karamooz, Elham Pfeiffer, Christopher D. McCarthy, James F. Trapp, Christopher L. Frazier, Sara K. Dodier, John E. Smith, Stephen M. |
author_facet | Schnell, Eric Harriff, Melanie J. Yates, Jane E. Karamooz, Elham Pfeiffer, Christopher D. McCarthy, James F. Trapp, Christopher L. Frazier, Sara K. Dodier, John E. Smith, Stephen M. |
author_sort | Schnell, Eric |
collection | PubMed |
description | Coronavirus disease (COVID-19), the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, is responsible for the 2020 global pandemic and characterized by high transmissibility and morbidity. Healthcare workers (HCWs) are at risk of contracting COVID-19, and this risk is mitigated through the use of personal protective equipment such as N95 Filtering Facepiece Respirators (FFRs). The high demand for FFRs is not currently met by global supply chains, potentially placing HCWs at increased exposure risk. Effective FFR decontamination modalities exist, which could maintain respiratory protection for HCWs in the midst of the current pandemic, through the decontamination and re-use of FFRs. Here, we present a locally-implemented ultraviolet-C germicidal irradiation (UVGI)-based FFR decontamination pathway, utilizing a home-built UVGI array assembled entirely with previously existing components available at our institution. We provide recommendations on the construction of similar systems, as well as guidance and strategies towards successful institutional implementation of FFR decontamination. |
format | Online Article Text |
id | pubmed-7276019 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cold Spring Harbor Laboratory |
record_format | MEDLINE/PubMed |
spelling | pubmed-72760192020-06-07 Homegrown Ultraviolet Germicidal Irradiation for Hospital-Based N95 Decontamination during the COVID-19 Pandemic Schnell, Eric Harriff, Melanie J. Yates, Jane E. Karamooz, Elham Pfeiffer, Christopher D. McCarthy, James F. Trapp, Christopher L. Frazier, Sara K. Dodier, John E. Smith, Stephen M. medRxiv Article Coronavirus disease (COVID-19), the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, is responsible for the 2020 global pandemic and characterized by high transmissibility and morbidity. Healthcare workers (HCWs) are at risk of contracting COVID-19, and this risk is mitigated through the use of personal protective equipment such as N95 Filtering Facepiece Respirators (FFRs). The high demand for FFRs is not currently met by global supply chains, potentially placing HCWs at increased exposure risk. Effective FFR decontamination modalities exist, which could maintain respiratory protection for HCWs in the midst of the current pandemic, through the decontamination and re-use of FFRs. Here, we present a locally-implemented ultraviolet-C germicidal irradiation (UVGI)-based FFR decontamination pathway, utilizing a home-built UVGI array assembled entirely with previously existing components available at our institution. We provide recommendations on the construction of similar systems, as well as guidance and strategies towards successful institutional implementation of FFR decontamination. Cold Spring Harbor Laboratory 2020-05-05 /pmc/articles/PMC7276019/ /pubmed/32511592 http://dx.doi.org/10.1101/2020.04.29.20085456 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator. |
spellingShingle | Article Schnell, Eric Harriff, Melanie J. Yates, Jane E. Karamooz, Elham Pfeiffer, Christopher D. McCarthy, James F. Trapp, Christopher L. Frazier, Sara K. Dodier, John E. Smith, Stephen M. Homegrown Ultraviolet Germicidal Irradiation for Hospital-Based N95 Decontamination during the COVID-19 Pandemic |
title | Homegrown Ultraviolet Germicidal Irradiation for Hospital-Based N95 Decontamination during the COVID-19 Pandemic |
title_full | Homegrown Ultraviolet Germicidal Irradiation for Hospital-Based N95 Decontamination during the COVID-19 Pandemic |
title_fullStr | Homegrown Ultraviolet Germicidal Irradiation for Hospital-Based N95 Decontamination during the COVID-19 Pandemic |
title_full_unstemmed | Homegrown Ultraviolet Germicidal Irradiation for Hospital-Based N95 Decontamination during the COVID-19 Pandemic |
title_short | Homegrown Ultraviolet Germicidal Irradiation for Hospital-Based N95 Decontamination during the COVID-19 Pandemic |
title_sort | homegrown ultraviolet germicidal irradiation for hospital-based n95 decontamination during the covid-19 pandemic |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276019/ https://www.ncbi.nlm.nih.gov/pubmed/32511592 http://dx.doi.org/10.1101/2020.04.29.20085456 |
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