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A randomized, open-label, Phase III study of obinutuzumab or rituximab plus CHOP in patients with previously untreated diffuse large B-Cell lymphoma: final analysis of GOYA
BACKGROUND: Rituximab (R) plus cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) is the current standard therapy for diffuse large B cell lymphoma (DLBCL). Obinutuzumab (G), a glycoengineered, type II anti-CD20 monoclonal antibody, has shown activity and an acceptable safety profile...
Autores principales: | Sehn, Laurie H., Martelli, Maurizio, Trněný, Marek, Liu, Wenxin, Bolen, Christopher R., Knapp, Andrea, Sahin, Deniz, Sellam, Gila, Vitolo, Umberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276080/ https://www.ncbi.nlm.nih.gov/pubmed/32505213 http://dx.doi.org/10.1186/s13045-020-00900-7 |
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