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Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review

pH-sensitive hydrogels have been developed greatly over the past few years. This has been possible due to the synthesis of new hydrogel systems with increased sensitivity – a sensitivity of up to 10(−5) pH units has already been established. Recently, pH-sensitive hydrogels have shown to be very use...

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Autores principales: Hendi, Asail, Umair Hassan, Muhammad, Elsherif, Mohamed, Alqattan, Bader, Park, Seongjun, Yetisen, Ali Kemal, Butt, Haider
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276332/
https://www.ncbi.nlm.nih.gov/pubmed/32581536
http://dx.doi.org/10.2147/IJN.S245743
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author Hendi, Asail
Umair Hassan, Muhammad
Elsherif, Mohamed
Alqattan, Bader
Park, Seongjun
Yetisen, Ali Kemal
Butt, Haider
author_facet Hendi, Asail
Umair Hassan, Muhammad
Elsherif, Mohamed
Alqattan, Bader
Park, Seongjun
Yetisen, Ali Kemal
Butt, Haider
author_sort Hendi, Asail
collection PubMed
description pH-sensitive hydrogels have been developed greatly over the past few years. This has been possible due to the synthesis of new hydrogel systems with increased sensitivity – a sensitivity of up to 10(−5) pH units has already been established. Recently, pH-sensitive hydrogels have shown to be very useful in biomedical applications, such as targeted cancer treatment and treatment of skin lesions. Prolonged drug release has been made available through the use of such hydrogels. The synthesis of pH-sensitive hydrogels is also quick and cost-effective. This review presents a background on the properties of pH-sensitive hydrogels and discusses some of the hydrogels with different sensitivity ranges and their possible applications. A range of synthesis processes have also been briefly introduced along with the fabrication of different structures such as microcantilevers and contact lenses.
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spelling pubmed-72763322020-06-23 Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review Hendi, Asail Umair Hassan, Muhammad Elsherif, Mohamed Alqattan, Bader Park, Seongjun Yetisen, Ali Kemal Butt, Haider Int J Nanomedicine Review pH-sensitive hydrogels have been developed greatly over the past few years. This has been possible due to the synthesis of new hydrogel systems with increased sensitivity – a sensitivity of up to 10(−5) pH units has already been established. Recently, pH-sensitive hydrogels have shown to be very useful in biomedical applications, such as targeted cancer treatment and treatment of skin lesions. Prolonged drug release has been made available through the use of such hydrogels. The synthesis of pH-sensitive hydrogels is also quick and cost-effective. This review presents a background on the properties of pH-sensitive hydrogels and discusses some of the hydrogels with different sensitivity ranges and their possible applications. A range of synthesis processes have also been briefly introduced along with the fabrication of different structures such as microcantilevers and contact lenses. Dove 2020-06-02 /pmc/articles/PMC7276332/ /pubmed/32581536 http://dx.doi.org/10.2147/IJN.S245743 Text en © 2020 Hendi et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Hendi, Asail
Umair Hassan, Muhammad
Elsherif, Mohamed
Alqattan, Bader
Park, Seongjun
Yetisen, Ali Kemal
Butt, Haider
Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review
title Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review
title_full Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review
title_fullStr Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review
title_full_unstemmed Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review
title_short Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review
title_sort healthcare applications of ph-sensitive hydrogel-based devices: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276332/
https://www.ncbi.nlm.nih.gov/pubmed/32581536
http://dx.doi.org/10.2147/IJN.S245743
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