Cargando…

Development of 13-Cys-BBR as an Agent Having Dual Action of Anti-Thrombosis and Anti-Inflammation

BACKGROUND: There is a correlation between tumor and inflammation. The activity of 13-[CH(2)CO-Cys(Bzl)-OBzl]-berberine (13-Cys-BBR) slowing tumor growth is higher than that of BBR. Whether the anti-inflammation activity of 13-Cys-BBR is higher than that of BBR remains unknown. There is a correlatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Guanyu, Wang, Tong, Zhang, Xiaoyi, Zhao, Shurui, Wang, Yaonan, Wu, Jianhui, Peng, Shiqi, Zhao, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276341/ https://www.ncbi.nlm.nih.gov/pubmed/32581515 http://dx.doi.org/10.2147/DDDT.S249228

Ejemplares similares

13-[CH(2)CO-Cys-(Bzl)-OBzl]-Berberine: Exploring The Correlation Of Anti-Tumor Efficacy With ROS And Apoptosis Protein
por: Li, Guanyu, et al.
Publicado: (2019)

Exploring the action of RGDV-gemcitabine on tumor metastasis, tumor growth and possible action pathway
por: Zhang, Xiaoyi, et al.
Publicado: (2020)

Gut microbiota specifically mediates the anti-hypercholesterolemic effect of berberine (BBR) and facilitates to predict BBR’s cholesterol-decreasing efficacy in patients
por: Wu, Chongming, et al.
Publicado: (2021)

Nano-scaled MTCA-KKV: for targeting thrombus, releasing pharmacophores, inhibiting thrombosis and dissolving blood clots in vivo
por: Zhao, Shurui, et al.
Publicado: (2019)

N-(3-hydroxymethyl-β-carboline-1-yl-ethyl- 2-yl)-l-Phe: development toward a nanoscaled antitumor drug capable of treating complicated thrombosis and inflammation
por: Wu, Jianhui, et al.
Publicado: (2017)

Docking of THPDTPI: to explore P-selectin as a common target of anti-tumor, anti-thrombotic and anti-inflammatory agent
por: Zhu, Haimei, et al.
Publicado: (2017)

Small molecule PZL318: forming fluorescent nanoparticles capable of tracing their interactions with cancer cells and activated platelets, slowing tumor growth and inhibiting thrombosis
por: Li, Shan, et al.
Publicado: (2015)

IQCA-TAVV: To explore the effect of P-selectin, GPIIb/IIIa, IL-2, IL-6 and IL-8 on deep venous thrombosis
por: Wu, Jianhui, et al.
Publicado: (2017)

RGDV-modified gemcitabine: a nano-medicine capable of prolonging half-life, overcoming resistance and eliminating bone marrow toxicity of gemcitabine
por: Liu, Wenchao, et al.
Publicado: (2019)

BCESA: a nano-scaled intercalator capable of targeting tumor tissue and releasing anti-tumoral β-carboline-3-carboxylic acid
por: Wu, Jianhui, et al.
Publicado: (2019)

Cu(2+)-RGDFRGDS: exploring the mechanism and high efficacy of the nanoparticle in antithrombotic therapy
por: Wu, Jianhui, et al.
Publicado: (2015)

ATIQCTPC: a nanomedicine capable of targeting tumor and blocking thrombosis in vivo
por: Xu, Xinyi, et al.
Publicado: (2017)

Discovery of DEBIC to correlate P-selectin inhibition and DNA intercalation in cancer therapy and complicated thrombosis
por: Chen, Haiyan, et al.
Publicado: (2017)

Design and development of ICCA as a dual inhibitor of GPIIb/IIIa and P-selectin receptors
por: Chen, Haiyan, et al.
Publicado: (2018)

Dimethyl 2,2′-[2,2′-(ethane-1,1-diyl)bis(1H-indole-3,2-diyl)]-diacetate: a small molecule capable of nano-scale assembly, inhibiting venous thrombosis and inducing no bleeding side effect
por: Wang, Yaonan, et al.
Publicado: (2018)

Reductive Dimerization of Macrocycles Activated by BBr(3)
por: Kijewska, Monika, et al.
Publicado: (2021)

Modifying tetramethyl–nitrophenyl–imidazoline with amino acids: design, synthesis, and 3D-QSAR for improving inflammatory pain therapy
por: Jiang, Xueyun, et al.
Publicado: (2015)

Optimization of BBR Congestion Control Algorithm Based on Pacing Gain Model
por: Yang, Shuang, et al.
Publicado: (2023)

Modifying ICCA with Trp-Phe-Phe to Enhance in vivo Activity and Form Nano-Medicine
por: Zhang, Xiaoyi, et al.
Publicado: (2020)

Estimation of the ion-trap assisted electrical loads and resulting BBR shift
por: Sharma, Lakhi, et al.
Publicado: (2018)

Dual-Modality ImmunoPET/Fluorescence Imaging of Prostate Cancer with an Anti-PSCA Cys-Minibody
por: Tsai, Wenting K, et al.
Publicado: (2018)

Improvement of RTT Fairness Problem in BBR Congestion Control Algorithm by Gamma Correction
por: Pan, Wansu, et al.
Publicado: (2021)

Genome-wide analysis of bZIP, BBR, and BZR transcription factors in Triticum aestivum
por: Ahad, Arzoo, et al.
Publicado: (2021)

Comparison of cytotoxicities and anti-allergic effects of topical ocular dual-action anti-allergic agents
por: Kim, Sung Il, et al.
Publicado: (2019)

Design and synthesis of nanoscaled IQCA-TAVV as a delivery system capable of antiplatelet activation, targeting arterial thrombus and releasing IQCA
por: Wu, Jianhui, et al.
Publicado: (2018)

Retraction: Genome-wide analysis of bZIP, BBR, and BZR transcription factors in Triticum aestivum
Publicado: (2022)

Characterization of a Unique Bordetella bronchiseptica vB_BbrP_BB8 Bacteriophage and Its Application as an Antibacterial Agent
por: Szymczak, Mateusz, et al.
Publicado: (2020)

ATIQCTPC targeting MMP-9: a key step to slowing primary tumor growth and inhibiting metastasis of lewis lung carcinoma in vivo
por: Wang, Yuji, et al.
Publicado: (2017)

Ether Cleavage Re-Investigated: Elucidating the Mechanism of BBr(3)-Facilitated Demethylation of Aryl Methyl Ethers
por: Kosak, Talon M, et al.
Publicado: (2015)

Improved motion correction of submillimetre 7T fMRI time series with Boundary-Based Registration (BBR)
por: Huang, Pei, et al.
Publicado: (2020)

Acyl‐Directed ortho‐Borylation of Anilines and C7 Borylation of Indoles using just BBr(3)
por: Iqbal, Saqib A., et al.
Publicado: (2019)

A pBBR1‐based vector with IncP group plasmid compatibility for Methylorubrum extorquens
por: Pöschel, Laura, et al.
Publicado: (2022)

Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy
por: Wang, Qi, et al.
Publicado: (2016)

Complexes of Ag and ZnO nanoparticles with BBR for enhancement of gastrointestinal antibacterial activity through the impacts of size and composition
por: Nguyen, Hue Thi, et al.
Publicado: (2023)

Molecular Mechanism for the Dual Alcohol Modulation of Cys-loop Receptors
por: Murail, Samuel, et al.
Publicado: (2012)

Cys–Cys and Cys–Lys Stapling of Unprotected Peptides Enabled by Hypervalent Iodine Reagents
por: Ceballos, Javier, et al.
Publicado: (2021)

RGD(F/S/V)-Dex: towards the development of novel, effective, and safe glucocorticoids
por: Jiang, Xueyun, et al.
Publicado: (2016)

ZGSO Spinel Nanoparticles with Dual Emission of NIR Persistent Luminescence for Anti-Counterfeiting Applications
por: Cai, Guanyu, et al.
Publicado: (2023)

Anti-Angiogenic and Anti-Scarring Dual Action of an Anti-Fibroblast Growth Factor 2 Aptamer in Animal Models of Retinal Disease
por: Matsuda, Yusaku, et al.
Publicado: (2019)

THROMBOSIS AND ANTI-COAGULANT THERAPY
Publicado: (1961)

Cannot write session to /tmp/vufind_sessions/sess_dqps5nba86u34kpgbpf6acarmq