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Obesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis

Experimental and molecular epidemiological studies indicate important roles for adipose tissue or high-fat diet (HFD) in tumor growth and metastasis. Gastric cancer (GC) possesses a metastatic predilection for the adipocyte-rich peritoneum. However, the precise molecular relevance of HFD in the peri...

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Detalles Bibliográficos
Autores principales: Li, Shuai, Wu, Teng, Lu, Yun-Xin, Wang, Jin-Xiang, Yu, Feng-Hai, Yang, Mei-Zhu, Huang, Yi-Jia, Li, Zhi-Jing, Wang, Sen-Lan, Huang, Ling, Lu, Lei, Tian, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276427/
https://www.ncbi.nlm.nih.gov/pubmed/32506038
http://dx.doi.org/10.1016/j.redox.2020.101596