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Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy
BACKGROUND: Sleep Disordered Breathing (SDB) is associated with a wide range of pathophysiological changes due, in part, to hypoxemia during sleep. We sought to identify gene transcription associations with measures of SDB and hypoxemia during sleep, and study their response to treatment. METHODS: I...
Autores principales: | Sofer, Tamar, Li, Ruitong, Joehanes, Roby, Lin, Honghuang, Gower, Adam C., Wang, Heming, Kurniansyah, Nuzulul, Cade, Brian E., Lee, Jiwon, Williams, Stephanie, Mehra, Reena, Patel, Sanjay R., Quan, Stuart F., Liu, Yongmei, Rotter, Jerome I., Rich, Stephen S., Spira, Avrum, Levy, Daniel, Gharib, Sina A., Redline, Susan, Gottlieb, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276515/ https://www.ncbi.nlm.nih.gov/pubmed/32512511 http://dx.doi.org/10.1016/j.ebiom.2020.102803 |
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