The inhibition of IL-2/IL-2R gives rise to CD8(+) T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia

Although most patients with COVID-19 pneumonia have a good prognosis, some patients develop to severe or critical illness, and the mortality of critical cases is up to 61.5%. However, specific molecular information about immune response in critical patients with COVID-19 is poorly understood. A tota...

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Detalles Bibliográficos
Autores principales: Shi, Hongbo, Wang, Wenjing, Yin, Jiming, Ouyang, Yabo, Pang, Lijun, Feng, Yingmei, Qiao, Luxin, Guo, Xianghua, Shi, Honglin, Jin, Ronghua, Chen, Dexi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276960/
https://www.ncbi.nlm.nih.gov/pubmed/32513989
http://dx.doi.org/10.1038/s41419-020-2636-4

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