Amikacin pharmacokinetic/pharmacodynamic in intensive care unit: a prospective database

BACKGROUND: Aminoglycosides have a concentration-dependent therapeutic effect when peak serum concentration (C(max)) reaches eight to tenfold the minimal inhibitory concentration (MIC). With an amikacin MIC of 8 mg/L, the C(max) should be 64–80 mg/L. This objective is based on clinical breakpoints a...

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Detalles Bibliográficos
Autores principales: Logre, Elsa, Enser, Maya, Tanaka, Sébastien, Dubert, Marie, Claudinon, Aurore, Grall, Nathalie, Mentec, Hervé, Montravers, Philippe, Pajot, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276966/
https://www.ncbi.nlm.nih.gov/pubmed/32514769
http://dx.doi.org/10.1186/s13613-020-00685-5

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