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The thermostability of the RTS,S/AS01 malaria vaccine can be increased by co-lyophilizing RTS,S and AS01
BACKGROUND: Developing thermostable vaccines is a challenge for pharmaceutical companies due to the inherent instability of biological molecules in aqueous solution. The problem is even more stringent in regions subjected to high temperatures in which protective cold chain is difficult to maintain d...
Autores principales: | Fortpied, Juliette, Collignon, Sylvie, Moniotte, Nicolas, Renaud, Frédéric, Bayat, Babak, Lemoine, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276967/ https://www.ncbi.nlm.nih.gov/pubmed/32513160 http://dx.doi.org/10.1186/s12936-020-03253-1 |
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