Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells

Studying posttranslational modifications classically relies on experimental strategies that oversimplify the complex biosynthetic machineries of living cells. Protein glycosylation contributes to essential biological processes, but correlating glycan structure, underlying protein, and disease-releva...

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Detalles Bibliográficos
Autores principales: Schumann, Benjamin, Malaker, Stacy Alyse, Wisnovsky, Simon Peter, Debets, Marjoke Froukje, Agbay, Anthony John, Fernandez, Daniel, Wagner, Lauren Jan Sarbo, Lin, Liang, Li, Zhen, Choi, Junwon, Fox, Douglas Michael, Peh, Jessie, Gray, Melissa Anne, Pedram, Kayvon, Kohler, Jennifer Jean, Mrksich, Milan, Bertozzi, Carolyn Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276986/
https://www.ncbi.nlm.nih.gov/pubmed/32325029
http://dx.doi.org/10.1016/j.molcel.2020.03.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276986/
https://www.ncbi.nlm.nih.gov/pubmed/32325029
http://dx.doi.org/10.1016/j.molcel.2020.03.030

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