Impact of Pus1 Pseudouridine Synthase on Specific Decoding Events in Saccharomyces cerevisiae

Pus1-dependent pseudouridylation occurs in many tRNAs and at multiple positions, yet the functional impact of this modification is incompletely understood. We analyzed the consequences of PUS1 deletion on the essential decoding of CAG (Gln) codons by tRNA(Gln)CUG in yeast. Synthetic lethality was ob...

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Detalles Bibliográficos
Autores principales: Khonsari, Bahar, Klassen, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277083/
https://www.ncbi.nlm.nih.gov/pubmed/32392804
http://dx.doi.org/10.3390/biom10050729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277083/
https://www.ncbi.nlm.nih.gov/pubmed/32392804
http://dx.doi.org/10.3390/biom10050729

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