Structure–Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by the Campylobacter jejuni Chemoreceptor Tlp3

Chemotaxis is an important virulence factor of the foodborne pathogen Campylobacter jejuni. Inactivation of chemoreceptor Tlp3 reduces the ability of C. jejuni to invade human and chicken cells and to colonise the jejunal mucosa of mice. Knowledge of the structure of the ligand-binding domain (LBD)...

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Detalles Bibliográficos
Autores principales: Khan, Mohammad F., Machuca, Mayra A., Rahman, Mohammad M., Koç, Cengiz, Norton, Raymond S., Smith, Brian J., Roujeinikova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277094/
https://www.ncbi.nlm.nih.gov/pubmed/32403336
http://dx.doi.org/10.3390/biom10050744

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