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Nailfold Videocapillaroscopy Is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients

Nailfold videocapillaroscopy (NVC) is an easy tool used for the assessment of patients with Raynaud’s phenomenon (RP) as possibly associated with systemic sclerosis (SSc). Recent insights have also highlighted its role in the diagnostic assessment of idiopathic inflammatory myopathies (IIMs). The ai...

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Autores principales: Sambataro, Domenico, Sambataro, Gianluca, Libra, Alessandro, Vignigni, Giovanna, Pino, Fabio, Fagone, Evelina, Fruciano, Mary, Gili, Elisa, Pignataro, Francesca, Del Papa, Nicoletta, Vancheri, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277171/
https://www.ncbi.nlm.nih.gov/pubmed/32344844
http://dx.doi.org/10.3390/diagnostics10050253
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author Sambataro, Domenico
Sambataro, Gianluca
Libra, Alessandro
Vignigni, Giovanna
Pino, Fabio
Fagone, Evelina
Fruciano, Mary
Gili, Elisa
Pignataro, Francesca
Del Papa, Nicoletta
Vancheri, Carlo
author_facet Sambataro, Domenico
Sambataro, Gianluca
Libra, Alessandro
Vignigni, Giovanna
Pino, Fabio
Fagone, Evelina
Fruciano, Mary
Gili, Elisa
Pignataro, Francesca
Del Papa, Nicoletta
Vancheri, Carlo
author_sort Sambataro, Domenico
collection PubMed
description Nailfold videocapillaroscopy (NVC) is an easy tool used for the assessment of patients with Raynaud’s phenomenon (RP) as possibly associated with systemic sclerosis (SSc). Recent insights have also highlighted its role in the diagnostic assessment of idiopathic inflammatory myopathies (IIMs). The aim of this study is to describe the diagnostic role of NVC in a series of 361 consecutive patients with interstitial lung disease (ILD). All the patients were assessed by clinical pulmonary and rheumatic examinations, blood exams, high-resolution computed tomography and NVC. NVC was considered positive only in the presence of avascular areas or giant capillaries, but also, the presence of bushy capillaries (BCs) was recorded. NVC was positive in 17.7% of ILD patients and in 78.1% of ILD patients associated with a diagnosis of connective tissue disease (CTD). In 25% of SSc-ILD patients, NVC proved necessary for a correct diagnosis. The presence of BCs and/or NVC positivity in ILD patients with normal levels of creatine phosphokinase is associated with amyopathic IIM, regardless the presence of RP. In conclusion, NVC is useful for the diagnostic assessment of incomplete forms of CTD and in amyopathic IIMs. NVC should be considered in the diagnostic assessment of ILD patients regardless of the presence of RP.
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spelling pubmed-72771712020-06-15 Nailfold Videocapillaroscopy Is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients Sambataro, Domenico Sambataro, Gianluca Libra, Alessandro Vignigni, Giovanna Pino, Fabio Fagone, Evelina Fruciano, Mary Gili, Elisa Pignataro, Francesca Del Papa, Nicoletta Vancheri, Carlo Diagnostics (Basel) Article Nailfold videocapillaroscopy (NVC) is an easy tool used for the assessment of patients with Raynaud’s phenomenon (RP) as possibly associated with systemic sclerosis (SSc). Recent insights have also highlighted its role in the diagnostic assessment of idiopathic inflammatory myopathies (IIMs). The aim of this study is to describe the diagnostic role of NVC in a series of 361 consecutive patients with interstitial lung disease (ILD). All the patients were assessed by clinical pulmonary and rheumatic examinations, blood exams, high-resolution computed tomography and NVC. NVC was considered positive only in the presence of avascular areas or giant capillaries, but also, the presence of bushy capillaries (BCs) was recorded. NVC was positive in 17.7% of ILD patients and in 78.1% of ILD patients associated with a diagnosis of connective tissue disease (CTD). In 25% of SSc-ILD patients, NVC proved necessary for a correct diagnosis. The presence of BCs and/or NVC positivity in ILD patients with normal levels of creatine phosphokinase is associated with amyopathic IIM, regardless the presence of RP. In conclusion, NVC is useful for the diagnostic assessment of incomplete forms of CTD and in amyopathic IIMs. NVC should be considered in the diagnostic assessment of ILD patients regardless of the presence of RP. MDPI 2020-04-25 /pmc/articles/PMC7277171/ /pubmed/32344844 http://dx.doi.org/10.3390/diagnostics10050253 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sambataro, Domenico
Sambataro, Gianluca
Libra, Alessandro
Vignigni, Giovanna
Pino, Fabio
Fagone, Evelina
Fruciano, Mary
Gili, Elisa
Pignataro, Francesca
Del Papa, Nicoletta
Vancheri, Carlo
Nailfold Videocapillaroscopy Is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients
title Nailfold Videocapillaroscopy Is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients
title_full Nailfold Videocapillaroscopy Is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients
title_fullStr Nailfold Videocapillaroscopy Is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients
title_full_unstemmed Nailfold Videocapillaroscopy Is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients
title_short Nailfold Videocapillaroscopy Is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients
title_sort nailfold videocapillaroscopy is a useful tool to recognize definite forms of systemic sclerosis and idiopathic inflammatory myositis in interstitial lung disease patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277171/
https://www.ncbi.nlm.nih.gov/pubmed/32344844
http://dx.doi.org/10.3390/diagnostics10050253
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